Title:

Genetic markers for the detection of quantitative trait loci with special consideration of body weight and fat

Creator:

Brockmann, G. A. ; Renne, U. ; Kopplow, K. ; Das, P.

Place of publishing:

Białowieża

Date issued/created:

1998

Description:

Mouse chromosome 11 was analyzed for the presence of quantitative trait loci (QTL) affecting body weight and fatness. Significant differences in allele frequencies (p<10-2) between two growth differentiated mouse lines DU6 and DUKs were proven at the marker loci D11Mit120, D11Mit125, and D11Mit126. In families which were derived from crosses between DU6 and DUKs cosegregation of genetic marker alleles and individual trait performance was analyzed. Variance analysis proved highly significant phenotypic differences between genotype groups (p<10-5), localized in one family in the chromosomal part between D11Mit236 and D11Mit126. These results were confirmed in independent families of parallel crosses. The detected chromosomal region affected both, body weight and fatness.

Type of object:

Journal/Article

Subject and Keywords:

body weight ; fatness ; incomplete ; mouse ; quantitative trait loci

Relation:

Acta Theriologica

Volume:

43

Issue:

Suppl. 5

Start page:

53

End page:

62

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

10.4098/AT.arch.98-47

Source:

click here to follow the link

Language:

eng ; Sum. eng.

Rights:

Rights Reserved - Free Access

Terms of use:

Copyright-protected material. May be used within the limits of statutory user freedoms

Digitizing institution:

Mammal Research Institute of the Polish Academy of Sciences

Original in:

Library of the Mammal Research Institute Polish Academy of Sciences

Projects co-financed by:

Programme Innovative Economy, 2010-2014, Priority Axis 2. R&D infrastructure ; European Union. European Regional Development Fund

Access:

Open