@misc{Dutkiewicz_Mariola_Strategy_2002,
 author={Dutkiewicz, Mariola and Ciesiołka, Jerzy},
 volume={56},
 number={1},
 copyright={Creative Commons Attribution BY-SA 4.0 license},
 journal={Biotechnologia, vol.56, 1 (2002)-.},
 howpublished={online},
 year={2002},
 publisher={Committee on Biotechnology PAS},
 publisher={Institute of Bioorganic Chemistry PAS},
 language={pol},
 abstract={Over the last decade, antisense oligodeoxynucleotides and ribozymes haveemerged as valuable biochemical tools and promising therapeutic reagents inmedicine. This review describes the basic principles of their use in the strategyof directed RNA degradation. The rules for the rational choice of targeted RNAsequences, the properties of available RNA cleaving tools, as well as the majorproblems that limit the effectiveness of this new technology, are discussed. Selected examples of the successful use of antisense oligonucleotides and ribozymesas antiviral agents are presented.},
 title={Strategy of directed RNA degradation and selected examples of its usein antiviral therapy},
 type={Text},
 URL={http://rcin.org.pl/Content/138381/PDF/POZN271_173736_biotechnologia-2002-no2-dutkiewicz.pdf},
 keywords={biotechnology},
}