@misc{Pawlik_Krzysztof_Bacterial_2002,
 author={Pawlik, Krzysztof and Kuczek, Katarzyna},
 volume={59},
 number={4},
 copyright={Creative Commons Attribution BY-SA 4.0 license},
 journal={Biotechnologia, vol.59, 4 (2002)-.},
 howpublished={online},
 year={2002},
 publisher={Committee on Biotechnology PAS},
 publisher={Institute of Bioorganic Chemistry PAS},
 language={pol},
 abstract={Many bacterial species use small chemical molecules as signaling factors.Signal molecules are released into the environment and once a threshold concentration level has been achieved, they trigger a response in the target cells.This system of cell-cell signaling, termed as “quorum sensing”, plays an important role in the coordination of the growth and other processes in bacterialpopulations. Two types of signaling molecules have been identified: (1) shortpeptides, common to Gram-positive bacteria and (2) carboxy-acid derivativescommonly utilised by Gram-negative bacteria. Bacteria of the genus Streptomycesutilize butyrolactones as signaling molecules and thus form a distinct groupamong Gram-positives. This review focuses on two model regulatory systemsbased on carboxy-acid derivatives; the regulation of bioluminescence in Vibriofisheri and the regulation of streptomycin biosynthesis in Streptomyces griseus.},
 type={Text},
 title={Bacterial small signaling molecules},
 URL={http://rcin.org.pl/Content/137709/PDF/POZN271_172915_biotechnologia-2002-no4-pawlik.pdf},
 keywords={biotechnology},
}