@misc{Murakami_Akira_Interaction_1996, author={Murakami, Akira and Nakaura, Misuzu and Uematsu, Hiroki and Fujimura, Naoko and Iwase, Reiko and Yamaoka, Tetsuji}, volume={35}, number={4}, copyright={Creative Commons Attribution BY-SA 4.0 license}, journal={Biotechnologia, vol.35, 4 (1996)-.}, howpublished={online}, year={1996}, publisher={Committee on Biotechnology PAS}, publisher={Institute of Bioorganic Chemistry PAS}, language={eng}, abstract={In order to evaluate the antisense effects in biological systems, the interaction of antisensemolecules with biological substances such as DNAs and human serum proteins was studied byfluorescence depolarization spectroscopy. When an antisense oligonucleotide anchoring fluorescein (F-AS) was mixed with DNAs or proteins, the anisotropy value changed, indicating thatantisense oligonucleotides appreciably interact with DNAs and serum proteins, and that suchinteraction may play important roles on antisense gene regulation.}, title={Interaction of Antisense Oligonucleotides with DNA and Proteins Studied by Fluorescence Polarization Spectroscopy}, type={Text}, URL={http://rcin.org.pl/Content/146564/PDF/POZN271_182242_biotechnologia-1996-no4-murakami.pdf}, keywords={biotechnology}, }