@misc{Adamiak_Dorota_A._Crystallization_1993,
 author={Adamiak, Dorota A.},
 volume={23},
 number={4},
 copyright={Creative Commons Attribution BY-SA 4.0 license},
 journal={Biotechnologia, vol.23, 4 (1993)-.},
 howpublished={online},
 year={1993},
 publisher={Committee on Biotechnology PAS},
 publisher={Institute of Bioorganic Chemistry PAS},
 language={pol},
 abstract={Crystallization is the most important and challenging step in the determination of the structure of biomolecules and macromolecules by diffraction methods.Macromolecules are extremely complex physical-chemical system whose properties vary as afunction of many environmental influences such as temperature, pH, ionic strength and solventcomposition. Therefore, a number of factors influencing macromolecule crystal growth ought tobe considered. Despite of considerable interest in the approaches allowing for continuous monitoring and setting of crystal growth conditions, in practice, numerous trials ought to be performedin order to obtain appropriate crystals characterized by their optimal geometrical parameters,crystallographic symmetry, unit cell and, most importantly, their high resolution.The vapour diffusion and the microdialysis methods are discussed as the most widely usedcrystallization methods of macromolecules.},
 type={Text},
 title={Crystallization of nucleic acids},
 URL={http://rcin.org.pl/Content/149099/PDF/POZN271_184603_biotechnologia-1993-no4-adamiak.pdf},
 keywords={biotechnology},
}