@misc{Kurpisz_Maciej_The_1993, author={Kurpisz, Maciej}, volume={21}, number={2}, copyright={Creative Commons Attribution BY-SA 4.0 license}, journal={Biotechnologia, vol.21, 2 (1993)-.}, howpublished={online}, year={1993}, publisher={Committee on Biotechnology PAS}, publisher={Institute of Bioorganic Chemistry PAS}, language={pol}, abstract={In this review contemporary trends in the application of monoclonal antibodies are presented.There is discussed antibody reengineering for humanization of mouse monoclonal antibodies toavoid anti-globulin reaction of patient. Recent modifications of antibody fragments are also outlined. The most common antigenic structures exposed to antibody attack are characterized. Someaspects of human monoclonal antibody production are briefly described. Three most promisingtherapeutic antibodies — bispecific antibodies, immunotoxins, and radiolabeled immunoconjugates — are presented.}, type={Text}, title={The application of monoclonal antibodies to medical treatment}, URL={http://rcin.org.pl/Content/155731/PDF/POZN271_189985_biotechnologia-1993-no2-kurpisz.pdf}, keywords={biotechnology}, }