Title:

THE ACTIVITY OF SUCCINIC DEHYDROGENASE IN GLIAL TUMORS

Creator:

Mossakowski, Mirosław Jan (1929–2001)

Publisher:

Lawrence Ks.

Date issued/created:

1962

Type of object:

Journal/Article

Subject and Keywords:

Succinic dehydrogenase ; glial tumors

Abstract:

Succinic dehydrogenase activity of astrocytic tumors of varying degrees of anaplasia was assessed by means of the tetrazolium reaction and compared with the activity in oligodendrogliomas and in the various elements of normal brain. Succinic dehydrogenase activity was present in all glial tumors examined. It increased with increasing anaplasia of the tumors. The SDA of oligoden¬droglioma, while high, was less than that of glioblastoma multiforme. The SDA in the cells of piloid astrocytoma appeared to be similar to that of normal astrocytes in white matter. SDA in the cells of gemistocytic astro¬cytoma, malignant glioma and glioblastoma multiforme exceeded considerably that in normal glia. Reactive glia also showed greater SDA than normal glia. There appears to be a relationship between the volume of cytoplasm con¬stituting the cel body and the amount of SDA exhibited by the cell.

Relation:

Journal of Neuropathology and Experimental Neurology

Volume:

21

Issue:

1

Start page:

137

End page:

146

Resource type:

Text

Detailed Resource Type:

Article (offprint)

Format:

pdf

Language:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open