Title:

Function of the liver and some biochemical indices during 3-hour extracorporeal perfusion in a patient with acute liver failure

Creator:

Rosnowska, Maria ; Olszewski, Waldemar ; Pomaski, Ireneusz ; i in.

Publisher:

PZWL

Place of publishing:

Warszawa

Date issued/created:

1972

Description:

[Translated from Diagnostyka Laboratoryjna vol.6, no 3, 1971]

Type of object:

Journal/Article

Abstract:

Some biochemical indices established during extra-corporeal perfusion ofpig liver with blood of the patient with acute liver failure were described. Theliver failure was a complication of viral hepatitis. There were abnormalitiesduring perfusion in acid-base equilibrium manifested by noncompensatedrespiratory alkalosis with hypopotassemia.The serum bilirubin level decreased while pyruvate and lactate concentrationsincreased. The serum alanine-aminotransferase activity was lower than in normals.The serum aspartate aminotransferase activity was higher and it appeared thatthis increase was caused by mitochondrial fraction. This suggestion was confirmedby the observation that in this condition the glutamate dehydrogenase activity(typical mitochondrial enzyme) was also elevated. During perfusion the increaseof glucose uptake by the patient was observed. The serum glucose concentrationshould be then continuously controlled.

Relation:

Polish Medical Journal

Volume:

11

Issue:

2

Start page:

360

End page:

367

Resource type:

Text

Detailed Resource Type:

Article

Format:

pdf

Language:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open