Tytuł:

Files for neuromuscular diseases (2010) - nr 36/10

Twórca:

Fidziańska-Dolot, Anna (1930–2015)

Współtwórca:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Miejsce wydania:

Warsaw

Data wydania/powstania:

2010

Opis:

Muscle segment examination in light & electron microscopy

Temat i słowa kluczowe:

Myopathy

Abstrakt:

A biopsy of quadriceps of a newborn baby was performed.Electronmicroscopy analysis revealed fibers characterized by disrupted structure of the contractileapparatus or even disintegration of myofibrils. Some of myofibers weretotally devoid of contractile apparatus and apoptotic nuclei, some of which were characterized by“ruffle-like” nuclear membraine were observed. Altered mitochondria were also seen.Ultrastructural image may suggest defects LMNA gene and deficiency in laminine A/C, what isassociated with a wide spectrum of diseases. Molecular analysis is recommended.

Typ zasobu:

Text ; Image

Szczegółowy typ zasobu:

Photography ; Files

Format:

pdf

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open