Subtitle:

Bioencapsulation of biologically active compounds in matrices obtained by sol-gel metod and its application

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

The encapsulation of biomolecules, e.g. enzymes, whole living cells or microorganisms in sol-gel derived monolithic silica, has been widely studied in recent years. Upon encapsulation, biomolecules retain their spectroscopic properties and biological activity. Sol-gel matrices are thermally and chemically stable and can be obtained in a variety of forms, such as optically transparent monoliths, granulates, microparticles or thin films. Sol-gel immobilization is characterized by physical entrapment without chemical modification. Immobilizing substances by physically trapping in individual pore of a matrix permits their molecules to be isolated and stabilized. The advantages of sol-gel encapsulated biologicals might give them applications such as optical and electrochemical sensors, diagnostic devices, catalysts, and even bioartificial organs. While the relatively large biomolecules are immobilized within the silica network, small ions or molecules are transported into the interior of the matrix.

Relation:

Biotechnologia, vol.76, 1 (2007)-.

Volume:

76

Issue:

1

Start page:

77

End page:

95

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:87151 ; IChB B-72

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open