Subtitle:

Bioconversion of trans-cinnamic acid to L-phenylalanine by Rhodotorula sp

Publisher:

Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN

Abstract:

The synthesis of the aromatic amino acid L-phenylalanine has received considerable attention in recent years due to its increasing importance as precursorto the dipeptide sweetener aspartame. Phenylalanine ammonia lyase (PAL), whichoccurs in yeast, catalyzes the nonoxidative deamination of L-Phe to trans-cinnamicacid (tCA), has industrial application in the synthesis of L-Phe. Superior producers of PAL are Rhodotorula sp. PAL is induced in yeast cell by the presence ofL-Phe, while glucose represses PAL synthesis. Different additives and conditionsduring inducing PAL: permeabilizing, reducing and stabilization agents, as wellas pH and temperature during bioconversion targeting to higher productivity ofL-Phe were discussed.

Relation:

Biotechnologia, vol.73, 2 (2006)-.

Volume:

73

Issue:

2

Start page:

117

End page:

129

Detailed Resource Type:

Artykuł

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:87574 ; IChB B-69

Source:

Biblioteka Instytutu Chemii Bioorganicznej PAN

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0

Terms of use:

-

Digitizing institution:

Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk

Original in:

Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk

Projects co-financed by:

Program Operacyjny Polska Cyfrowa, lata 2014-2020, Działanie 2.3 : Cyfrowa dostępność i użyteczność sektora publicznego; środki z Europejskiego Funduszu Rozwoju Regionalnego oraz współfinansowania krajowego z budżetu państwa

Access:

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