Object structure
Title:

Biokonwersja kwasu frans-cynamonowego do L-fenyloalaniny przez drożdże z rodzaju Rhodotorula

Subtitle:

Bioconversion of trans-cinnamic acid to L-phenylalanine by Rhodotorula sp

Creator:

Gientka, Iwona ; Błażejak, Stanisław ; Duszkiewicz-Reinhard, Wanda

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2006

Subject and Keywords:

biotechnology

Abstract:

The synthesis of the aromatic amino acid L-phenylalanine has received considerable attention in recent years due to its increasing importance as precursorto the dipeptide sweetener aspartame. Phenylalanine ammonia lyase (PAL), whichoccurs in yeast, catalyzes the nonoxidative deamination of L-Phe to trans-cinnamicacid (tCA), has industrial application in the synthesis of L-Phe. Superior producers of PAL are Rhodotorula sp. PAL is induced in yeast cell by the presence ofL-Phe, while glucose represses PAL synthesis. Different additives and conditionsduring inducing PAL: permeabilizing, reducing and stabilization agents, as wellas pH and temperature during bioconversion targeting to higher productivity ofL-Phe were discussed.

Relation:

Biotechnologia, vol.73, 2 (2006)-.

Volume:

73

Issue:

2

Start page:

117

End page:

129

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; IChB B-69

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open

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