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Wpływ sorbitolu na sieciowanie kolagenu osierdzia wieprzowego w procesie fotooksydacji
Subtitle:The influence of sorbitol on photooxidation-mediated crosslinking of porcine pericardial collagen
Creator:Wisowski, Grzegorz ; Olczyk, Krystyna ; Koźma, Ewa M. ; Jura-Półtorak, Agnieszka ; Olczyk, Paweł ; Kuźnik-Trocha, Kornelia
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:Collagen is one of the most useful biomaterials. The medical application of collagen tissues requires specific fixation procedures. Dye-mediated photooxidation is a method of the new collagen crosslink formation. In this study, the influence of sorbitol on the extent of porcine pericardial collagen crosslinking was investigated. The collagen modification was estimated on the basis of pericardial susceptibility to pepsin digestion. The hydrolysate components were characterized electrophoretically. The significant collagen crosslinking was found in all photooxidized samples, in comparison with the untreated ones. However, the most enhanced collagen modification was observed for pericardium photo- oxidized with 0,5% and 0,9% sorbitol, as compared to the samples fixed without sorbitol.
Relation:Biotechnologia, vol.71, 4 (2005)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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