Title:

The influence of sorbitol on photooxidation-mediated crosslinking of porcine pericardial collagen

Subtitle:

The influence of sorbitol on photooxidation-mediated crosslinking of porcine pericardial collagen

Creator:

Wisowski, Grzegorz ; Olczyk, Krystyna ; Koźma, Ewa M. ; Jura-Półtorak, Agnieszka ; Olczyk, Paweł ; Kuźnik-Trocha, Kornelia

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2005

Subject and Keywords:

biotechnology

Abstract:

Collagen is one of the most useful biomaterials. The medical application of collagen tissues requires specific fixation procedures. Dye-mediated photooxidation is a method of the new collagen crosslink formation. In this study, the influence of sorbitol on the extent of porcine pericardial collagen crosslinking was investigated. The collagen modification was estimated on the basis of pericardial susceptibility to pepsin digestion. The hydrolysate components were characterized electrophoretically. The significant collagen crosslinking was found in all photooxidized samples, in comparison with the untreated ones. However, the most enhanced collagen modification was observed for pericardium photo- oxidized with 0,5% and 0,9% sorbitol, as compared to the samples fixed without sorbitol.

Relation:

Biotechnologia, vol.71, 4 (2005)-.

Volume:

71

Issue:

4

Start page:

189

End page:

196

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; IChB B-67

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open