Subtitle:

Micromanagement

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Type of object:

Journal/Article

Abstract:

MicroRNAs (miRNAs) are an abundant group of endogenous small (—22) noncoding RNAs, found both in plants and animals. The total number of sequences encoding miRNA in genomes of these organisms is estimated to be of all genes. miRNAs derive from longer precursor transcripts which adopt a fold- back structure. Mature miRNAs are incorporated into ribonucleoprotein complexes miRNPs and take part in negative control of genes’ expression by cleavage of mRNAs or inhibition of the translation. miRNAs influence a great range of biological processes, such as cell proliferation, stem cell maitenance, timing of cell fate in developmental process, organ morphogenesis, programmed cell death and fat metabolism.

Relation:

Biotechnologia, vol.70, 3 (2005)-.

Volume:

70

Issue:

3

Start page:

144

End page:

164

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:91947 ; IChB B-66

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open