Title:

Files for neuromuscular diseases (2007) - nr 42/07

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2007

Description:

Muscle segment examination in light & electon microscopy

Subject and Keywords:

Cogenital myopathy

Abstract:

A 40-year-old patient with congenital myopathy was examined. A biceps sinister biopsy wasperformed.Electronmicroscopy analysis revealed presence of normal diameter muscle fibers. They werecharacterized by preserved myofibrils and sub-membranous located cell nuclei but damage to nuclearenvelope and ultrastructural abnormalities within nuclei were observed. In some fibres focal ruptureof contractile apparatus was observed.Also fibers of small diameter characterized by decay of contractile apparatus were seen.The accumulation of a large amount of autophagal structures was observed. In some fibres almostthe entire muscle fiber was filled by autophagal structures.

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open