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Koźma, Ewa M. ; Głowacki, Andrzej ; Olczyk, Krystyna ; Wisowski, Grzegorz ; Olczyk, Paweł ; Jura-Półtorak, Agnieszka ; Nawrat, Zbigniew
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:Photooxidation is a method of tissue fixation in the construction ofbioprostheses. This process leads to the tissue protein crosslinking under lightand dye. In the present study, the influence of methylene blue and methylenegreen on the effectiveness of pulmonary valve and aorta collagen modificationwas evaluated on the basis of photooxidized tissues sensitivity to pepsin digestion. The components of tissue hydrolysates were characterized electrophoretically. The tissues photooxidized in the presence of employing dyes showed increased resistance to enzymatic degradation in comparison to the unfixed ones.However, methylene green was more effective in valve and aorta collagencrosslinking. Hydrolysates of the tissues fixed in the presence of mentioned dyedisplayed decrease in collagen a chains and their aggregates’ content.
Relation:Biotechnologia, vol.61, 2 (2003)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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