Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Description:

Muscle segment examination in light microscopy

Abstract:

Diagnosis: 2 years after heart transplant. Date of the sample collection: April 1, 2004. Muscle: biceps sin. Most of the muscle fibers are of the correct diameter, single smaller ones, clearly visible in H-E staining, irregular small, multi-shaped defects showing a different “pink” color in the Gomori trichrome. In numerous fibers, the displacement of the nuclei towards the center of the fibers is visible. In staining with diaphoresis and LDH, numerous activity concentration of various sizes and shapes are visible, mainly in type 2 fibers. In DHB staining, losses of activity corresponding to enzymatic concentrations in NADH and LDH. In the ATP-asa staining at pH 9.4 in type 2 fibers, numerous minor losses in activity within the fibers. In ATPase staining with pH 4.3, activity losses in single type 1 fibers. Conclusions: the image may correspond to myopathy with a disorder of sarcomere proteins, requires evaluation in M-E.

Detailed Resource Type:

Photography ; Files

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:135792

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open