Title:

The expression of WAP-Fuc gene in genotypes of transgenic farmanimals - effectiveness of transgenesis with the use of DNAmicroinjection

Subtitle:

The expression of WAP-Fuc gene in genotypes of transgenic farmanimals - effectiveness of transgenesis with the use of DNAmicroinjection

Creator:

Jura, Jacek ; Smorąg, Zdzisław ; Gajda, Barbara ; Kareta, Wiesław ; Kopchick, John J. ; Kelder, Bruce ; Prieto, Pedro A.

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2003

Subject and Keywords:

biotechnology

Abstract:

There are two principal applications oftransgenic animals. Best known andmost advanced application is to use transgenic animals (called bioreactors ormolecular farms) for the production of various proteins or biopolymers of medical significance. The second application concerns efforts to improve the productivity traits of breeding animals. We have worked out methods which allow somatic cloning of mammals and gene knockout methods. These methods havebeen developing very rapidly in recent years and their efficiency will soon beimproved to the extent that they will become profitable. For the time being,DNA microinjection with all its disadvantages, remains the principal method ofproducing transgenic bioreactors. In this paper, the effectiveness of productionoftransgenic rabbits, goats and pigs with the use of WAP-Fuc gene construct ispresented.

Relation:

Biotechnologia, vol.60, 1 (2003)-.

Volume:

60

Issue:

1

Start page:

216

End page:

222

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open