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Gut-Winiarska, Monika ; Szewczyk, Bogusław
Publisher:Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Date issued/created: Subject and Keywords: Abstract:This paper aims to evaluate different forms of the enzyme-linkedimmunosorbent assays (ELISA) for the detection of virus-specific antibodies andfocuses on factors which may influence the diagnostic reliability of such tests.The differences between competitive and non-competitive ELISAs are described, with reference to the influence of the antigen, the conjugated antibody, and the test sample on the test results. Attention is drawn to interference, which may result in false positive or false negative test results. The use ofmonoclonal antibodies and discriminatory tests is briefly discussed. Diagnosticreliability is described for tests that are used in monitoring or eradicationprogrammes, emphasising the consequences of false negative or false positiveresults.
Relation:Biotechnologia, vol.54, 3 (2001)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Library of Institute of Bioorganic Chemistry PAS
Language: Language of abstract: Temporal coverage: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use: Digitizing institution:Institute of Bioorganic Chemistry of the Polish Academy of Science
Original in:Institute of Bioorganic Chemistry of the Polish Academy of Science
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