Subtitle:

Immunotechnology of enzymes and antibodies

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

In this article, the special catalytic proteins-called abzymes and synzymesare presented. Abzymes are defined as antibodies with catalytic properties.Similarly, synzymes are semisynthetic amino acid copolymers, also having catalytic properties. The production of these two kinds of catalytic proteins is different. Abzymes are made by the immunological methods using specific organichaptens. Synzymes can be the products of, among others, mutagenesis and areproduced by genetic engineering. It has been also suggested that the productsof synzym hydrolysis could be a source of haptens for the production ofabzymes. In conclusion it was stated that a new specialization in biotechnologycould emerge. We called it “immunotechnology”. To these two groups ofimmuno-products the plastic antibodies, which are the molecular imprinting ofdeterminants of the natural antibodies on polymer template, can be added. So,they are completely synthetic products. They are characterised by strong chemical and physical stability under drastic environmental conditions.

Relation:

Biotechnologia, vol.54, 3 (2001)-.

Volume:

54

Issue:

3

Start page:

86

End page:

96

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:138867 ; IChB B-50

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open