Title:

Files for neuromuscular diseases (2011) - nr 4/11-2

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2011

Description:

Muscle segment examination in light and electron microscopy

Subject and Keywords:

Dystrophy - facial-scopulo-brachial

Abstract:

A 31-year-old patinet with suspected facioscopulohumeral muscular dystrophy (FHSD) was examined. A biopsy of biceps dexter was performed. In some fibres electronmicroscopy analysis revealed changes in the sarcomeres structure and a local loss of myofibrils. Abnormal, folded nuclei penetrating deep into the cytoplasm with large gap between inner and outer nuclear membrane were observed. Few autophagal srtuctures were seen. The image of specimen suggests nucleopathy. Asseessment of activity of lamin A and ermetrin is advisable.

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open