Gene Therapy by Means of Liposomes
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
One great advantage of liposome-encapsulated genes for gene therapy is its safeness. But ahortcoming is its low transfection efficiency. To overcome this shortage, we devised cationicarge unilamellar vesicles for efficient entrapment and transfer of the gene for its expression.Recently, we devised a simple method to prepare cationic multilameller large vesicles. By use)f these vesicles, malignant glioma in an experimental model was successfully cured.
Biotechnologia, vol.35, 4 (1996)-.
0860-7796 ; oai:rcin.org.pl:146550 ; IChB B-31
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Nov 9, 2020
Nov 9, 2020
42
https://rcin.org.pl/publication/182203
Edition name | Date |
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Gene Therapy by Means of Liposomes | Nov 9, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan