Subtitle:

Staphylokinase — a new approach in the treatment of vascular disease

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

Staphylokinase is a new promising therapeutic agent with an expanding clinical applicationin the treatment of vascular disease. In the present paper the authors discuss the biochemicaland physiological properties of the recombinant protein. The methods and techniques of proteinsynthesis, isolation and purification, including the genetic engineering approaches are criticallysummarized. The emphasis is put onto the critical review of the experiments concerning theuse of staphylokinase in thrombotic models in experimental animals. Moreover, we discuss thepotential role and advantages of staphylokinase over the other thrombolytic agents in the treatment of cardiovascular disease in humans

Relation:

Biotechnologia, vol.34, 3 (1996)-.

Volume:

34

Issue:

3

Start page:

43

End page:

51

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:146809 ; IChB B-30

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open