Exciting new opportunities in embryo cloning have been made possible by recent studies onthe interaction of the donor nucleus with the recipient cytoplasm following embryo reconstruction. The purpose of this paper is to review information regarding the co-ordination of nuclearand cytoplasmic events during embryo reconstruction, in particular the direct and indirect effectsof maturation/meiosis/mitosis promoting factor (MPF), upon the transferred nucleus. These willbe discussed in relation to DNA replication, the maintenance of correct ploidy, the occurrenceof chromosomal abnormalities and development of reconstructed embryos. Although this reviewis primarily concerned with the reconstruction of mammalian embryos, specific examples fromamphibians will also be cited.
Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.
Nov 13, 2020
Nov 13, 2020
|The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos||Nov 13, 2020|
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.
Zimny, J. Czaplicki, A. Menke-Milczarek, I. Oleszczuk, S. Sowa, S.
Buchowiecka, Alicja Bielecki, Stanisław