Subtitle:

p53 — tumour suppressor gene

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

The structure of p53 tumour suppressor gene and molecular mechanisms of p53 functionare characterized. The effects of the p53 protein on gene transcription, control of the cell cycle,DNA repair and synthesis, cell differentiation, and programmed cell death are discussed. Besidesclinical implications of inactivation of the p53 gene in the pathogenesis, diagnosis, and therapyof human cancer are mentioned.

Relation:

Biotechnologia, vol.30, 3 (1995)-.

Volume:

30

Issue:

3

Start page:

91

End page:

103

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:147666 ; IChB B-26

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open