Tytuł:

Studies of heart ultrastructure in various diseases by prof A. Fidziańska-Dolot: storage disease - 77/08

Twórca:

Fidziańska-Dolot, Anna (1930–2015)

Twórca instytucjonalny:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Współtwórca:

Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Miejsce wydania:

Warsaw

Data wydania/powstania:

2008

Opis:

Electron microscopy analysis of the heart biopsy

Temat i słowa kluczowe:

Ceroidolipofuscinosis ; storage disease ; Mitral and tricuspid valve regrigation.

Abstrakt:

Mitral and tricuspid valve regurgitation.Ceroidolipofuscinosis.Ultrastructural analysis revealed the presence of abundant osmophilic granular material deposits in cardiomyocytes.This material was surrounded by a membrane.Within these deposits lipid vacuoles were observed.Characteristic granular deposits were also present in the vicinity or inside the mitochondria.Numerous myelin-like bodies were visible in the karyoplasm.Cardiomyocyte nuclei in the examined material were characterized by an irregular shape and numerous invaginations in the nuclear envelopes. Ruptures of the nuclear envelopes were often observed.

Typ zasobu:

Text ; Image

Szczegółowy typ zasobu:

Files ; Photography

Format:

pdf

Język:

pol ; eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open