Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases
Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases
Electron microscopy analysis of the heart biopsy
Significant changes in sarcomere pattern were observed. The ultrastructural evaluation revealed also changes in the course of myofibrils and their disorganization, often a total loss of myofibrils was noticed. Quite numerous lipid droplets were visible. The cardiomyocyte nuclei were characterized by abnormal shape, the nuclear envelope was corrugated, forming numerous invaginations, and broken in some parts. Some nucleicontained cellular organelles inside them. Focally, especially in the vicinity of cardiomyocyte nuclei deposits of lipofuscin were seen. A large accumulation of mitochondria was observed in sarcoplasm. Some of them showed ultrastructuralchanges - abnormal arrangement of mitochondrial cristae was visible.
Creative Commons Attribution BY 4.0 license
Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Jan 21, 2021
99
https://rcin.org.pl/publication/189706
Edition name | Date |
---|---|
uszkodzenie mięśnia sercowego - 33/11 | Feb 1, 2022 |
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)