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Studies of heart ultrastructure in various diseass by prof A. Fidziańska-Dolot: laminopathy - 26/08
Creator:Fidziańska-Dolot, Anna (1930–2015)
Institutional creator:Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases
Contributor: Place of publishing: Date issued/created: Description:Electron microscopy analysis of the heart biopsy
Subject and Keywords: Abstract:Ultrastructural analysis revealed proper sarcomere pattern, but changes in the myofibrils arrangement and their significant disorganization and/or atrophy we reevident (Fig.1-5). Features of laminopathy were observed .Cardiomyocyte nuclei of different shapes were seen, nuclear envelope was often corrugated, with numerous indentations.Many nuclei showed breaks in the nuclear membrane ,which was associated with penetration of cell organelles into the nuclei (Figs.6-17). Focally,plentiful glycogen deposits (Figs.18-20). and some vacuoles (Figs.21-23) were present Abundant fibrosis was observed in the extracellular space (Figs.2426).
Resource type: Detailed Resource Type: Format: Language: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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