Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

J. Korthals, lek.

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Encephalomalacia inveterata. Autopsy examination of 64-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and Van Gieson's method.A specimen taken from the malcia focus revealed necrosis destroying the white matter and cortex, with a partially preserved fine layer. The focus was in an advanced stage of organization. In the central part, remnants of disintegrating tissue, macrophages and a dense capillary network, rich in collagen fibers, were visible. Besides, numerous smaller foci forming post infarct cavities, perivascular sinuses, and old glial scars were observed in the white matter. Nerve cells in the cortex showed features of fatty degeneration and chronic disease. Lymphocytic cells, sometimes macrophages, were present in the vicinity of the focus of malacia, next to highly atherosclerotic vessels..

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:197146

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open