Department of Experimental and Clinical Neuropathology MMRI
Clinical, anatomical and histological diagnosis
Histological diagnosis: Encephalomalaciae recentes hemisphae riutriusque et cerebelli invetera. Autopsy examination of 57-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with cresyl-violet, Heidenhain and Van Gieson's method.In both cerebral hemispheres, in the area of middle cerebral arteries vascularization a foci of fresh malacia were found. In the left hemisphere, they involved the early basal ganglia, superior temporal ganglia, and middle temporal ganglia. In the right hemisphere, they occupied the middle and inferior temporal gyrus and the inferior parietal lobe. Perivascular cavities and blood-infiltrated tissue were also visible in the striatum. The foci of malacia were in the phase of very early necrosis or leucocytic infiltration. Heindenhain staining showed myelin damage within the foci as well as in its borders. In the cerebellum, an old degenerative focus in the stage of advanced organization was found. Symptomatic infiltrates were observed in the meninges. Large atherosclerotic lesions were seen in the vessels. Besides, features of congestion and edema were found.
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Jul 9, 2021
58
https://rcin.org.pl/publication/232855
Edition name | Date |
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opis nr 139/65 | Feb 1, 2022 |