Title:

File of histopathological evaluation of nervous system diseases (1964) - nr 167/64

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Osetowska, Ewa Prof.

Place of publishing:

Warsaw

Date issued/created:

1964

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Neoplasms- gliomas

Abstract:

Histological diagnosis: Astrocytoma partim astroblastoma malignum.Autopsy examination of 81-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.Both sampled foci were conglomerates of neoplastic tissue, hemorrhage, and necrosis. In the center of the fairly well-demarcated foci, a partially preserved, partially disintegrating, neoplastic tissue was visible among the disintegrated blood cells and macrophages. This tissue was polymorphic, but with respect to different foci, in individual islands it retained a fairly similar structure. Most common were foci of chromatin cells, with large astrocyte-like nuclei and elongated protoplasm. These cells formed characteristic perivascular arrangements. There were 2-3 mitotic figures in the field of view. In other clusters, the cells were spindle-shaped, with abundant round hyperchromatic cells. In fields cut transversely, these arrangements assumed the character of small round cells. Fields with a mixed cell population appeared less frequently. Often, entire sections of the tumor utricle were obliterated by structure following necrosis. The vessels within and surrounding the tumor were vitreously altered. Astrocytic infiltrates, consisting of regular mast cells, hyperplastic astrocytes and proliferating astrocytes, were disseminated in and outside the fields of necrosis; in addition, clusters of astrocyte-like macrophages with a morphology consistent with Opalski's cells were found

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open