Title:

Badania termodynamiczne, strukturalne i biologiczne niekanonicznych form DNA i RNA

Creator:

Szabat, Marta

Date issued/created:

2017

Description:

Praca doktorska została wykonana w Zakładzie Chemii i Biologii Strukturalnej Kwasów Nukleinowych

Location:

Poznań

Subject and Keywords:

biochemia

Abstract:

DNA exists as a double helical structure, called B helix, which is the most commonstructure. In native RNA, double-stranded helical regions are short (on average 5–7 basepairs long) and RNA contains many different structural motifs, such as: hairpins,symmetrical and asymmetrical single or double nucleotide bulges, internal loops. Thepolymorphic nature of nucleic acids allows to adopt a variety of structures depending onthe sequences, the local environment, the presence of molecules or chemicalmodifications. For examples, DNA and RNA can form parallel-stranded duplexes, triplehelical structures (triplexes) or four-stranded structures (quadruplexes).

Start page:

1

End page:

205

Resource type:

Text

Detailed Resource Type:

PhD Dissertations

Format:

application/pdf

Language:

pol

Language of abstract:

pol ; eng

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

-

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open