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Complexes of PR-10 proteins with plant hormones: crystallographic and biophysical studies
Creator: Date issued/created: Description:Scientific adviser: Prof. Mariusz Jaskólski
Location: Abstract:This doctoral thesis presents studies of pathogenesis related proteins of class 10 (PR-10). Sofar no specific function has been assign to this group. The PR-10 family consist of small,intracellular biomolecules of acidic character, whose expression is elevated in response to bioticand abiotic stress. The characteristic fold of PR-10 proteins, which consists of seven antiparallelβ strands wrapped around an extended, C-terminal α helix, creates a globular protein with alarge, hydrophobic cavity, which is capable of accommodating small-molecule ligands. Althoughmany constitutively expressed plant proteins exhibit the PR-10 fold, they are not typicallyrelated to pathogenesis. A variety of different ligand classes, including cytokinins, flavonoids andsteroids, have been demonstrated so far (via crystallographic and biophysical methods) tooccupy the PR-10 cavity.
Start page: End page: Resource type: Detailed Resource Type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use: Digitizing institution:Institute of Bioorganic Chemistry of the Polish Academy of Science
Original in:Institute of Bioorganic Chemistry of the Polish Academy of Science
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