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Is Acute failure of Adrenals an Important Factor Limiting Recovery from cerebral Ischemia ?
Subtitle:Cerebral Microcirculation and Metabolism / ed. by J Cervos-Navarro & E. Fritschka
Creator:Kapuściński, Andrzej (1937–2018)
Contributor:Pluta, Ryszard ; Mossakowski, Mirosław J. (1929–2001)
Publisher: Place of publishing: Date issued/created: Description: Type of object: Subject and Keywords:Cerebral Ischemia ; Cerebral Microcirculation
Abstract:Systemic arterial hypotension is a well-known factor limiting recovery from cerebral ischemia. The majority of studies have mentioned its noxious effect on reperfusion of cerebral microcirculation and have dealt with methods of counteracting it rather than with its mechanism. Several authors assume an impairment of the vasomotor centers in midbrain and hypothalamus as a basie event in the mechanism of hypotension (1,2,9). The necessity of pharmacological support of blood pressure during the hypotensive period in the extensive research on complete cerebral ischemia by means of several experimental models turned our attention to the possible role of the lack of endogenic vasopressor substances, among other reasons. The purpose of this study was to characterize alterations of systemie arterial pressure during and after complete cerebral ischemia. and to correlate them with changes of noradrenaline concentration in the blood, as well as to analyze other factors participating in the mechanisms of ischemic-postischemic hypotension.
Resource type: Detailed Resource Type: Format: Language: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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