Subtitle:

13nd International Congress of Paediatrics,29 August- 4 September 1971, Wien , Osterreich. Proceedings . Immunology Vol.4

Contributor:

Czarnocki, D. ; Mossakowski, Mirosław ; Rap, Zbigniew ; Weinrauder, Halina

Publisher:

Verlag der Wiener Medizinischen Akademie

Description:

381-386, il..

Type of object:

Book/Chapter

Abstract:

Considering the resemblance of immunological mechanismus between graft-reject-reaction and Experimental Allergic Encephalitie /E.A.E„/ our Ezperiment aimed at inducing a more durable tolerance in E.A.E. In our investigation, the rabbits received 6-Mercaptopurin intravenously, concurrently with the classical immunisation with brain suspension and Freund full adjuvant and for 18 days after. We hoped in this way to eliminate more effectively the specifio immunological clones. After stopping this drug the new sensibilisation of treated rabbits gave a much weaker response both from clinical and histological point of fiew than in control animals. The problems concerning the wider aignificance and the mechanism of the acquired tolerance needs futher conside-ration.

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

oai:rcin.org.pl:69693

Language:

ger

Language of abstract:

eng

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open