Object

Title: AKTYWNOŚĆ ENZYMÓW OKSYDO - REDUKCYJNYCH W TKANCE GLEJOWEJ HODOWANEJ IN VITRO W ZMIENNEJ ATMOSFERZE GAZOWEJ

Subtitle:

ACTIVITY OF REDOX ENZYMES IN GLIAL TISSUE CULTIVATED IN VITRO IN VARIABLE GAS ATMOSPHERE

Contributor:

Polska Akademia Nauk. Zakład Neuropatologii

Publisher:

Państwowy Zakład Wydawnictw Lekarskich

Place of publishing:

Warszawa

Abstract:

The behavior of redox enzyme activities in glial cultures under the influenceof variable content of atmospheric oxygen was studied.Activity of these enzymes is dependent on the content of oxygen in the atmosphere,solubility of oxygen in the medium, age of the culture, and -type ofglial cells.The greatest drop in enzymatic activity was observed under conditions ofcomplete hyperoxia and anoxia.The effect of intermediate states of hypoxia and hyperoxia on the activity ofdehydrogenases was not distinct.Young cultures, from 2 to 3 week exhibited greatest drops in enzymatic activities.The character of the enzymatic reactions and the distribution of activities indifferent types of glial ceils were the same as under conditions of normal gasatmosphere.SDH, NAD, GHD, G«P DH, G-6-P DH and LDH exhibited the greatest dropin activity.The enzymatic activity of all the studied dehydrogenases was directly dependenton the functional state and morphologic picture of the glial cells.

Relation:

Neuropatologia Polska

Volume:

5

Issue:

1

Start page:

125

End page:

134

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:69657

Language:

pol

Language of abstract:

eng ; rus

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

- ; Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at:

Digitizing institution:

Mossakowski Medical Research Center PAS

Original in:

Library of the Mossakowski Medical Research Center PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open

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