Metadata language
Postresuscitation changes of blood-brain barrier permeability and their possible pathogenetic importance. ; Postreanimacjonnye izmenenija pronicaemosti gematoencefalicheskogo bar'iera i ich vozmoźnoe patogeneticheskoe znachenie
Creator:Gannushkina I.V. ; Mossakowski, Mirosław Jan (1929 - 2001) i in.
Publisher: Place of publishing: Date issued/created: Type of object: Subject and Keywords:Blood, proteins -- metabolism ; Immunoglobulins-- metabolism ; Brain diseases-- physiopathology ; Blood-brain barrier -- physiology
Abstract:Experiments were conducted on, rats, with temporary (10 min) clamoing of the thoracic vascular bundle and subsequent resuscitation to study the premeability of the blood-brain barrier (BBB) to plasma albumins and globulins and to blood plasma immunoglobulins in different stages of the postresuscitation period> Mild increase of BBB premeability was detected 3 minutes after the beginning of recirculation. Promeability increased markedly in 24 hours and continued growing by the 72nd hour. At s 1-3 hour interval in recirculation the BBB was closed. The obtained results discodse the mechanisms of the development of autoimmune cerebral disorders in on organism that experienced cardiac arrest and resuscitation.
Relation:Patołogicheskaja Fizjologija i Eksperimentalnaja Terapija
Volume: Start page: End page: Resource type: Detailed Resource Type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use:Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
Projects co-financed by: Access: