@misc{Pietrucha_Tadeusz_Staphylokinase_1996, author={Pietrucha, Tadeusz and Watała, Cezary}, volume={34}, number={3}, copyright={Creative Commons Attribution BY-SA 4.0 license}, journal={Biotechnologia, vol.34, 3 (1996)-.}, howpublished={online}, year={1996}, publisher={Committee on Biotechnology PAS}, publisher={Institute of Bioorganic Chemistry PAS}, language={pol}, abstract={Staphylokinase is a new promising therapeutic agent with an expanding clinical applicationin the treatment of vascular disease. In the present paper the authors discuss the biochemicaland physiological properties of the recombinant protein. The methods and techniques of proteinsynthesis, isolation and purification, including the genetic engineering approaches are criticallysummarized. The emphasis is put onto the critical review of the experiments concerning theuse of staphylokinase in thrombotic models in experimental animals. Moreover, we discuss thepotential role and advantages of staphylokinase over the other thrombolytic agents in the treatment of cardiovascular disease in humans}, title={Staphylokinase — a new approach in the treatment of vascular disease}, type={Text}, URL={http://rcin.org.pl/ichb/Content/146809/PDF/POZN271_182456_biotechnologia-1996-no3-pietrucha.pdf}, keywords={biotechnology}, }