@misc{Krawczyk_Beata_Optimalization_2007, author={Krawczyk, Beata and Lewandowski, Krzysztof}, volume={77}, number={2}, copyright={Creative Commons Attribution BY-SA 4.0 license}, howpublished={online}, year={2007}, publisher={Committee on Biotechnology PAS}, publisher={Institute of Bioorganic Chemistry PAS}, language={pol}, abstract={Macrorestriction analysis of genomic DNA followed by pulsed-field gel electrophoresis (REA-PFGE) has become the “gold standard” for molecular typing. In recent years, some alternative techniques have been successfully applied. However, there is still a need for a new method which may appear to be less complex, cheaper, and have a power of discrimination at least similar to that of REA-PFGE. Recently, we showed the performance and convenience of a novel assay, based on the fingerprinting of bacterial genomes by amplification of DNA fragments surrounding rare restriction sites (ADSRRS-fingerprinting), for its potential usefulness in epidemiological investigations.}, title={Optimalization and validation of ADSRRS-fingerprinting}, type={Text}, URL={http://rcin.org.pl/ichb/Content/87118/PDF/POZN271_113503_biotechnologia-2007-no2-krawczyk.pdf}, keywords={biotechnology}, }