@misc{Kurzyńska-Kokorniak_Anna_Reverse_2002,
 author={Kurzyńska-Kokorniak, Anna and Jaskólski, Mariusz and Figlerowicz, Marek},
 volume={56},
 number={1},
 copyright={Creative Commons Attribution BY-SA 4.0 license},
 journal={Biotechnologia, vol.56, 1 (2002)-.},
 howpublished={online},
 year={2002},
 publisher={Committee on Biotechnology PAS},
 publisher={Institute of Bioorganic Chemistry PAS},
 language={pol},
 abstract={Human immunodeficiency virus (HIV), the causative agent ofAIDS, belongsto the particularly dangerous and, as a result, the most extensively studied viruses. Until now no effective method protecting against this pathogen has beendeveloped. The major problem is the unusual genetic variability of HIV, whichhelps the virus to escape from immunological response and to produce drug-resistant mutants. Most of the collected data suggest that HIV-encoded reverseiransciiptase (HIV RT) is the main facto.- responsible for the continuos generation of new viral variants. There are two primary mechanisms involved in thegeneration of HIV mutants: high error prone replication and genetic RNA recombination. In this article both processes are discussed in detail.},
 title={Reverse transcriptase as the enzyme responsible for the genetic variability of human immunodeficiency virus (HIV)},
 type={Text},
 URL={http://rcin.org.pl/ichb/Content/138379/PDF/POZN271_173734_biotechnologia-2002-no2-kurzynska.pdf},
 keywords={biotechnology},
}