Metadata language
Mechaniczne uszkodzenia komórek zwierzęcych w bioreaktorach
Subtitle:Mechanical damage of animal cells in bioreactors
Creator:Jankowski, Tomasz ; Grajek, Włodzimierz
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:Fluid-mechanical damages of shear sensitive animal cells due to forces generated by mediaagitation and aeration are reviewed. In anchorage-dependent cultures grown in a stirred bioreactor the cell damage is caused by small turbulent eddies of size of the microcarrier beads andby collision between microcarriers and against the impeller and the stationary parts of bioreactor.In the freely suspended cells grown in stirred or air-lift reactors the cell damage is due mainlyto air bubble breakup. The mechanical damages can be limited by an increase of kinematicviscosity of fluid and reduction of the local energy dissipation rate. Biological aspects of shearstress are also discussed.
Relation:Biotechnologia, vol.22, 3 (1993)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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