Biosafety in laboratory and biotechnology industry
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The paper deals with biosafety aspects of handling EFB Class 2 microorganisms in industry. It presents the summary of the results of the collaborative studies taken to determine air and surface contamination levels during GMT laboratory work, the results of studies of contamination by microorganisms around industrial fermenters and during downstream processing and also the safety of four commercial air filters used on exhaust lines of fermenters. Furthermore, ten years of experience with biosafety at Organon was reviewed. In conclusion one can state that biotechnological processes with Class 2 microorganisms can be performed at the same level of safety as work in the laboratory, if Good Microbiological Technique is strictly adhered to and suitable physical containment is applied. This holds also for recombinant DNA organisms of the corresponding risk class.
Biotechnologia, vol.9-8, 3-2 (1990)-.
0860-7796 ; oai:rcin.org.pl:183776 ; IChB B-06
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Apr 23, 2021
Apr 19, 2021
41
https://rcin.org.pl/ichb/publication/218346
Edition name | Date |
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Bezpieczeństwo biologiczne w laboratorium i przemyśle biotechnologicznym | Apr 23, 2021 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan