Promotor:Prof. UAM dr hab. Jan Milecki ; Praca przedstawiona Radzie Naukowej Wydziału Chemii Uniwersytetu im. A. Mickiewiczacelem uzyskania stopnia naukowego doktora nauk chemicznych
Copper(I) Catalyzed Alkyne-Azide Cycloaddition strongly influenced onDNA-based synthesis of novel oligonucleotides derivatives. Possibility of creating new kindof chain linkage, 1,4-disubstituted 1,2,3-triazole replacement of native phosphodiester, devoidof negative charge and nuclease resistant, appears to be extremely interesting. This allows todesign new class of nucleic acid analogues, similar in its DNA-mimicking properties toPNA’s
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Jul 21, 2021
Jun 30, 2021
39
https://rcin.org.pl/ichb/publication/231199
Edition name | Date |
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Acykliczne analogi oligonukleotydów otrzymywane metodą chemii „Click” | Jul 21, 2021 |