New strategies for application of plasmid and viral vectors in gene therapy
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The success of gene therapy depends on development of efficient and safe delivery vectors. Recently, significant progress has been achieved in application of various non-viral delivery methods and numerous modified viral vectors for experimental gene therapy. Some of those vectors have been also successfully used in clinical trials of gene therapy. Further progress in this still promising, although not-fulfilling all expectations, treatment is dependent on the careful evaluation of the modes of transgene delivery and regulation of transgene expression in the diseased tissues. In this review the current progress in development of some of the tools for therapeutic gene transfer is discussed.
Biotechnologia, vol.78, 3 (2007)-.
0860-7796 ; oai:rcin.org.pl:75474 ; IChB B-74
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
Jul 22, 2019
2355
https://rcin.org.pl/ichb/publication/99289
Edition name | Date |
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Nowe strategie wykorzystania wektorów plazmidowych i wirusowych w terapii genowej | Oct 2, 2020 |
Stopa, Magdalena Dulak, Józef Józkowicz, Alicja
Stopa, Magdalena Dulak, Józef Józkowicz, Alicja
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Kucharzewska, Paulina Zagórska, Anna Leja, Justyna Jaźwa, Agnieszka Gozdecka, Małgorzata Józkowicz, Alicja Dulak, Józef
Gołda, Sławomir Kucharzewska, Paulina Cisowski, Jarosław Florczyk, Urszula Zagórska, Anna Jaźwa, Agnieszka Łoboda, Agnieszka Józkowicz, Alicja Dulak, Józef