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File of histopathological evaluation of nervous system diseases (1966) - nr 125/66
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Vascular disaeses - encephalomacia recens
Abstract:Histological diagnosis: Encephalomacia multiplices recens et inveterata. Autopsy examination of 78-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, PAS and van Gieson method.In the corpus callosum there was a fresh focus of malacia covering a very large area. The tissue within the focus was poorly stained, loosened, and single macrophages were seen in some places. Numerous amyloid globules were found in the marginal parts of the fornix. In the basal ganglia numerous foci of malacia were seen, partially destroying the amygdala, globus pallidus, and internal capsule. The foci were in the stage of dissection or glial-mesodermal organization. In addition, perivascular cavities were found. Large atherosclerotic lesions were seen in the vessels. Almost all nerve cells showed features of fatty degeneration.PAS- positive material was present in macrophages, amyloid globules and degenerated nerve cells. Features of edema and congestion were observed throughout the CNS.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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