Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

L.Iwanowski, doc

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Ischemia diffusa hemisphaeri dextri cerebri. Hyperaamia et oedema cerebri. Atrophia cerebri simplex. Arteriosclerosis gradu mediocri, arteriosclerosis gradu maioris. Autopsy examination of 77-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, Heidenhain and Van Gieson's method.In specimens from the right cerebral hemisphere, the predominant change were spongy changes of the superficial layers of the central cortex and insula and gliosis of the white matter of the entire hemisphere. Within the basal nuclei diffuse gliosis, stimulated microglia and increased gliosis were seen, as well as areas of vacuolation and moderate hypertrophy with preserved layering. Many nerve cells, both in the cortex and pons contained lipofusin deposits. Features of edema and congestion were observed throughout the brain. There were no macrophage reaction anywhere. Numerous vitreous changes of arterioles were found, sometimes leading to the closure of their lumen. The whole picture suggests acute ischemia within the right middle cerebral artery superimposed on chronic vascular changes..

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:197020

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open