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File of histopathological evaluation of nervous system diseases (1964) - nr 80/64
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Place of publishing: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Vascular disaeses - encephalomacia
Abstract:Histological diagnosis: Encephalomalacia cerebri. Arteriosclerosis cerebri.Autopsy examination of 77-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.A focus of diffuse necrosis was seen in the frontal lobe, destroying the white matter and cortex over a large area, preserving the fine layer almost completely. The focus was covered with macrophages, with little vascular reaction, causing complete tissue disintegration in places, and a spongy state in places. The cortex showed extensive neuronal atrophy and obliterated layered pattern. The activation and proliferation of the glia was evident, especially in the vicinity of the focus. Small macrophage infiltrates were evident in the meninges; vessels were hypertrophic with fibrous changes.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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