RCIN and OZwRCIN projects

Object

Title: File of histopathological evaluation of nervous system diseases (1963) - nr 22/63

Date issued/created:

1963

Resource type:

Text

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Kahl, J. dr

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Focii encephalomalaciae multiplices partim cum haemorrhagies secundaris.Autopsy examination of 63-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson.Vascular foci of various age were found in all areas examined. In specimens from the left hemisphere in the temporal region, a focus of malacia during macrophage dissection phase involving the hippocampus was present. Numerous capillaries were penetrating into the focus. In some areas, the tissue was completely disintegrated, with large clusters of macrophages. At the periphery, the tissue was narcotically altered and stimulated glial cells as well as remnants of nerve cells were visible. Within the circumscribed focus, hemorrhagic lesions were evident, most severe in its central part. An inflammatory reaction with marked macrophage involvement was observed in the adjacent meninges. The oldest foci of malacia were seen in the insula and its nearest surroundings including the junction of temporal and parietal lobes. In the anterior part of the temporal lobe, necrotic lesions were fresh, with quite numerous scattered leukocytes visible in the tissue and around the vessels. In the basal ganglia there were small vessels filled with leukocytes, in larger ones leukocytes were adhering to vessels walls. In their vicinity there were fields of necrotic tissue with leukocytes, the spaces around the vessels were dilated. In places, foci of further disintegration with few macrophages, surrounded by stimulated glia with hypertrophic forms of astroglia were observed. Pseudocalcium deposits were accumulated in the walls of the globus pallidus vessels.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:209384

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open

Object collections:

Last modified:

Feb 1, 2022

In our library since:

Sep 9, 2021

Number of object content downloads / hits:

16

All available object's versions:

https://rcin.org.pl/imdik/publication/246228

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Edition name Date
opis nr 22/63 Feb 1, 2022
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