Department of Experimental and Clinical Neuropathology MMRI
Clinical, anatomical and histological diagnosis
Histological diagnosis: Hydrocephalus in the course of toxoplasmosis.Autopsy examination of 10-days-old infant was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, cresyl-violet, Heidenhain and Kluver method.The cerebellar and brainstem structures were normal. The nuclei of the basal ganglia were deformed and covered with a thick layer of subcortical glia. The temporal and occipital cortex were fairly well formed with minor secondary cellular changes. The remaining part of the pallium was a bladder, whose thin wall was composed of glial tissue covered with mesodermal fibers. The inner surface of the bladder also had a glial-mesodermal structure and corresponded to a layer of subependymal glia. Lymphocytic-macrophage inflammatory infiltrates were seen in the stem meninges. Numerous calcified formations corresponding to terminal colonies of toxoplasmas were found in the supra- and subependymal glia.
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Sep 14, 2021
38
https://rcin.org.pl/imdik/publication/246302
Edition name | Date |
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opis nr 161/63 | Feb 1, 2022 |